The basis of generic Fildena® XXX in online store without prescription and this phenomenon with all variety of its clinical and morphological features on a single model of molecular genetic modulations in the cell.

Progestins are derivatives of Fildena Xxx 100 mg for sale OTC and testosterone this group of Fildena Xxx online order Fortune Health Care and drugs include two compounds — Danazol and Pregnin, widely used in clinical practice. First has expressed antigonadotropnym and androgenic effect, the second has mostly progesterone effect on the endometrium and mammary glands, very weak "Central" effect. In addition to differences in systemic effects of these medicines are also observed qualitative differences in the clinical manifestations of their actions. If the Danazol causes atrophy of the endometrium and the establishment of amenorrhea on the background of 119 manifestations of hyperandrogenism, the pregnin stimulates the secretory transformation of the endometrium and in an adequate regimen ensures maintaining a proper menstrual cycle.

Another important characteristic of GS in the reproductive system is expressed by the ability of its morphological substrate to respond to corrective antiproliferative hormonal effects, causing the suppression of best place to buy Fildena Xxx 100 mg online and cell proliferation, and the resulting regression of the morphological changes. A natural consequence of this impact is the restoration of normal menstrual cycle or stop it. Plenty of examples of this — regression of glandular hyperplasia of the endometrium as a result of prolonged hormone therapy progestinami, or more clear evidence of this effect was reversible growth suppression of uterine fibroids or regression after the introduction of analogues of gonadotropin-releasing hormone or antiprogestogen (Mifepristone), which provides the possibility of making savings of surgical interventions.

Possible common pathogenesis may explain their high compatibility in different organs of best place to buy Fildena® XXX 100 mg online and the reproductive system, with incidence of hyperplastic changes of the endometrium.

Both isomers re widely distributed in body tissues, but some regularities can be noted. Thus, ER-α is determined in the endometrium, mammary tissue, the stroma of the ovaries and the hypothalamus. ER-β located in the kidney tissue, bones, heart, lungs, colon, prostate and vascular endothelium.

Hirsutism as a symptom of enhanced hair growth on the male type and the manifestation of how can buy Fildena® XXX online and the excessive influence of androgen (dihydrotestosterone) on the hair follicle of the skin occurs in patients with the syndrome SCA only some time after menarche and may continue to grow in its intensity, even against the background the continuing right of the menstrual cycle.

Endometrial polyps and cervical canal endometrial Polyps and cervical canal, as seen from the above classification of endometrial hyperplasia, is not considered by who experts as hyperplastic phenomenon. This interpretation of best place to buy Fildena® XXX 100 mg online and the pathology of polyps of the mucous membrane of the uterine cavity does not seem to us indisputable. Endometrial polyps are formed in the process of proliferation of the epithelium of the glands of the basal layer of the endometrium. Originally proliferating glands and surrounding stroma to form polypoidy growth on a broad basis. Subsequently developing the leg with different thickness, which are involved in newly formed blood vessels and muscle fibers. On histological structure distinguish two types of endometrial polyps: polyps containing elements of a functioning endometrium and polyps, composed of glands basal type. First to respond to estrogenic stimulation and the effect of progesterone

In these two different completeness of generic Fildena® XXX in online store without prescription and reporting the nature of the problem responses of doctors from different generations — tomorrow's doctor and experienced specialist in a mirror reflected our incomplete understanding of one of the most difficult syndromes clinical endocrinology.

In 1989 N. Kaplan described of Fildena Xxx online order Fortune Health Care and abdominal obesity, suggesting the concept of "deadly Quartet" (obesity, diabetes of the 2nd type, arterial hypertension, hypertriglyceridemia), which develops in MS and significantly increases the mortality from cardiovascular diseases. With the development of the methodological base of the research, allowed to establish the direct determination of insulin in the blood, it was possible to identify key metabolic disorders in the form of hyperinsulinemia and insulin resistance from the fat and muscle tissue. In 1992, S. M. Haff ner 57 offers the term "syndrome of insulin resistance" (IR), believing that in this way most accurately reflected the pathogenesis of the "deadly Quartet".

There is no need to enumerate a large number progestinami drugs and treatment regimens of endometriosis, since this issue is fairly well described in the literature and manuals. When selecting the optimal scheme of generic Fildena Xxx in online store without prescription and hormonal therapy of endometriosis, the preference should be given to compounds with a pronounced effect antigonadotropnym in the absence of androgenic side effects, given the need for long-term therapy. The other requirement of the scheme of hormonal therapy is the possibility of saving and maintaining a proper menstrual cycle when a sufficiently long treatment time (a year or more). These requirements meet Chlormadinone acetate and a new progestin — Dienoguest.

After laparoscopic resection of best place to buy Fildena Xxx 100 mg online and the ovaries observed to restore the correct rhythm of the menstrual cycle, after 3 months a significant decrease of manifestations hirsutula syndrome.

In this regard, of how can buy Fildena Xxx online and particular importance is the possibility of long-term application with the medical purpose herbal remedies, with diaminobutane effect on the anterior pituitary and by inhibiting the excessive secretion of prolactin, in the absence of any significant side effects.

It should be emphasized the diversity found in the ovaries of change, which determines the diversity of generic Fildena® XXX in online store without prescription and clinical and biochemical manifestations of the syndrome. Found that hyperplasia of the theca due to chronic stimulation of LH and accompanied by an increase in androgen production. Arising in connection with this vnutritrekovye high concentration of androgen and can lead to accelerated follicle atresia, as well as thickening of the ovarian capsule.

With these considerations in mind, it is important to emphasize that, for example, to compensate for the lack of yellow body, any progestin, but for fully adequate therapy should choose the drug which, in addition to the main effect, to alleviate the symptoms accompanying hormonal imbalance (hyperandrogenism, mastodinia, etc.).